• Link to live app:  DUEshiny
• Updated Feb 20, 2019.

Interested in Phase One trials? What is the trade-off between potential clinical benefit and potential adverse outcomes? This explorer peers into the total knowledge situation where the joint distribution of thresholds for response and for toxicity is completely known. As the utility values change, and as the joint distribution changes (for example to make it bimodal or trimodal), we may discover some surprising results about optimal doses.